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    The drug’s label defines the condition as the onset of sexual characteristics before age 8 in girls and before 9 in boys.“Uses beyond those contained in the approved label are considered unapproved uses,” company spokesman Morry Smulevitz said in an email.At 21, a surgeon replaced her deteriorated jaw joint.She’s been diagnosed with degenerative disc disease and fibromyalgia, a chronic pain condition. None of it made sense to her until she discovered a community of women online who describe similar symptoms and have one thing in common: All had taken a drug called Lupron.Alexander Fleming wrote in a memo for the drug approval file that it was “regrettable” that the panel approved the drug after minimal study.One study followed 22 children for just six months, Fleming said.Luckily, there are several locations locally that provide thrilling experiences in the art of illusion.

    In interviews and in online forums, women who took the drug as young girls or initiated a daughter’s treatment described harsh side effects that have been well-documented in adults.Women who used Lupron a decade or more ago to delay puberty or grow taller described the short-term side effects listed on the pediatric label: pain at the injection site, mood swings, and headaches.Yet they also described conditions that usually affect people much later in life.Meanwhile, pediatricians and industry researchers are criticizing doctors for using Lupron to help kids with normally timed puberty grow taller, an “off-label” practice that was shown more than a decade ago to cause harm.Off-label prescribing is legal and common, but means doctors are using drugs in ways the FDA did not determine to be safe and effective.

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