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    Development of a ciliary muscle driven accommodating intraocular lens

    The two materials form a single lens with a variable index of refraction, similar to a gradient index (GRIN) lens. et al., “Prospective visual evaluation of apodized diffractive intraocular lenses,” J Cataract Refract Surg, vol. In one implementation, the bag is made from a material with a higher index of refraction than the optically clear medium. A minimally invasive surgical procedure, resulting in an ability of the intraocular lens to accommodate, makes this device well suited not only to fix cataracts, but also for other less serious conditions such as presbyopia. Because of its ability to fit through small incisions, the injectable accommodating intraocular lens can be used with minimally invasive surgical techniques, making recovery time for a patient more rapid and reducing surgical complications. et al., “Visual function after monocular implantation of apodized diffractive multifocal or single-piece monofocal intraocular lens: randomized prospective comparison,” J Cataract Refract Surg, vol. Furthermore, the materials used along the visual axis of the device, such as parylene, desirably are stable—despite light exposure for decades—and do not change color over time. For compatibility with subsequent ocular procedures, the bag and optically clear medium are constructed of materials that are not damaged by a Nd: YAG laser.

    development of a ciliary muscle driven accommodating intraocular lens-50

    et al., “Development of a ciliary muscle-driven accommodating intraocular lens,” J Cataract Refract Surg, vol. The anterior ridge is particularly important for surgical cases when only a small capsulotomy is performed because lens epithelial cells may migrate to the anterior surface of the capsule causing visual disturbances.

    In the drawings, like reference numbers indicate identical or functionally similar elements. 1 is a cross section of a human eye in a non-accommodated (left side) and an accommodated state (right side). 2 is a cross section of a human eye with a traditional capsulotomy of the prior art. 3 is a cross section of a human eye with a minimally invasive peripheral capsulotomy in accordance with an embodiment. 4 is a cross section of a human eye with an injectable accommodating intraocular lens being injected into the capsule in accordance with an embodiment. 5 is a cross section of a human eye with an injectable accommodating intraocular lens being inflated with an optically clear medium inside the capsule in accordance with an embodiment. 6 is a cross section of a human eye with a peripheral incision and an injectable accommodating intraocular lens inserted into the lens capsule in a non-accommodated (left side) and an accommodated state (right side) state in accordance with an embodiment. 7 is an injectable accommodating intraocular lens in accordance with an embodiment. 8 is the injectable accommodating intraocular lens with a flexible central portion in accordance with an embodiment. 9 illustrates a wagon wheel-shaped frame port having needle-pierceable portions in accordance with an embodiment. 10 is a chart illustrating experimentally determined thicknesses of a valves that self-seal the lens at different pressures. 11 is a chart illustrating needle diameters found to fill injectable accommodating intraocular lenses in a specific amount of time. 12 is a picture of a lens with an injection tube before dissolvable mold material has been removed in accordance with an embodiment. 13 is a close-up picture of a 1.5 μm thick parylene lens with its injection system cauterized in accordance with an embodiment. 14 is a picture of a lens with mold material dissolved and an injection system attached in accordance with an embodiment. 15 is a picture of a parylene lens filled with 20 centistoke silicone fluid in accordance with an embodiment. 16 is a picture of an exemplary composite parylene-on-silicone lens in accordance with an embodiment. 17 illustrates an exemplary air bubble capture mechanism in accordance with an embodiment. 18 illustrates a silicone intraocular lens manufacturing process using molds in accordance with an embodiment. 19A is a picture of a 30 μm silicon elastomer shell fused on two halves around the equator and entry valve in accordance with an embodiment. Once inserted, the accommodating intraocular lens deforms in response to the natural focusing mechanism of the existing ciliary muscle to change focus in a manner similar to a human lens.

    Further features and advantages of the present invention, as well as the structure and operation of various embodiments of the present invention, are described in detail below with respect to the accompanying drawings. After insertion, the intraocular lens is inflated with the clear medium to a target dioptric power.

    A straight or stepped slit in the patch can allow a blunt needle to more easily access the interior of the lens. Therefore, no surgically invasive procedure is required to modify the power of the lens after implantation.

    International Search Report and Written Opinion, Jul. Air Bubble Capture One implementation of an intraocular lens device has a feature that facilitates capture of air bubbles.

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